Table 6.
Regression analysis for prediction of insulin resistance within T2DM cases
| Univariable
|
Multivariable
|
|||||||
|---|---|---|---|---|---|---|---|---|
| P | OR | 95% CI | P | OR | 95% CI | |||
| Age (years) | 0.662 | 1.020 | 0.934 | 1.113 | ||||
| Gender | 0.624 | 1.345 | 0.412 | 4.388 | ||||
| BMI (kg/m2) | 0.889 | 0.986 | 0.811 | 1.199 | ||||
| FH | 0.488 | 1.560 | 0.445 | 5.474 | ||||
| Triglycerides (mg/dL) | 0.699 | 1.194 | 0.485 | 2.943 | ||||
| Total cholesterol (mg/dL) | 0.831 | 1.153 | 0.311 | 4.269 | ||||
| HDL-C (mg/dL) | 0.950 | 1.142 | 0.018 | 7.010 | ||||
| LDL-C (mg/dL) | 0.828 | 0.918 | 0.426 | 1.980 | ||||
| Fasting blood glucose (mg/dL) | 0.035 | 1.392 | 1.023 | 1.893 | 0.247 | 1.054 | 0.964 | 1.153 |
| FPI (IU/mL) | 0.005 | 2.940 | 1.991 | 9.634 | 0.018 | 2.241 | 1.269 | 11.633 |
| HOMA-IR | 0.008 | 1.321 | 1.075 | 1.624 | 0.023 | 1.288 | 1.001 | 8.179 |
| HBA1C (%) | 0.710 | 1.456 | 0.201 | 10.528 | ||||
| rs1801278 (GA+AA) | 0.043 | 2.536 | 1.030 | 6.249 | 0.018 | 0.895 | 0.429 | 1.867 |
Abbreviations: BMI, body mass index; FH, family history; FPI, fasting plasma insulin; HDL-C, high-density lipoprotein cholesterol; HOMA, homeostatic model assessment; IR, insulin resistance; LDL-C, low-density lipoprotein cholesterol; T2DM, type 2 diabetes mellitus.