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. 2018 Sep 28;11:6339–6350. doi: 10.2147/OTT.S178001

Figure 1.

Figure 1

miR-1225-5p is downregulated in glioblastoma and correlated with patient survival.

Notes: (A) The expression of miR-1225-5p in glioblastoma cell lines (A172, SW1783, U87, LN-229, SW1088, and T98G) and normal human astrocytes was measured by reverse transcription PCR (RT-PCR) and normalized against U6. (B) The expression of miR-1225-5p in five normal brain tissues and 44 glioblastoma samples was measured by RT-PCR and normalized against U6. (C) The expression of miR-1225-5p in stage I–II and III–IV glioblastoma tumors was measured by RT-PCR and normalized against U6. (D) The correlation between the miR-1225-5p level (low or high) with overall patient survival was assessed with Kaplan–Meier analysis. **P<0.01 vs astrocytes; **P<0.01 or ***P<0.001 vs indicated group.