Table 1.

Baseline characteristics of included cohorts

Study name	Ethnicity	Country	No of participants	Follow-up (years)	Men (%)	Age (years)	SBP (mm Hg)	Hypertension (%)	Antihypertensive drugs (%)	rs4988235 frequency (%)
										CC	CT	TT
CGPS	White	Denmark	74 219	0	45	57	140	20	20	6	36	58
WGHS	White	USA	19 743	4	0	54	126	13	13	11	38	51
GESUS	White	Denmark	14 815	0	46	57	142	10	23	6	36	58
NHS	White	USA	11 287	26	0	53	NA	9	NA	14	41	45
ARIC (white)	White	USA	8233	6	47	54	118	29	19	9*	39*	52*
ARIC (African-American)	African	USA	1889	6	36	53	127	55	41	74*	25*	2*
HPFS	White	USA	6914	24	100	55	NA	22	NA	18	39	43
INTER99	White	Denmark	6514	5	49	46	130	31	7	6	36	57
D.E.S.I.R.	White	France	3378	9	50	47	131	35	9	22	49	30
Rotterdam Study	White	Netherlands	3215	7	41	66	136	54	27	9	39	52
MDCS	White	Sweden	3199	17	40	56	139	53	14	6†	33†	61†
GLACIER	White	Sweden	2763	10	37	45	124	19	4	7	36	58
MESA	Mixed	USA	2424	10	47	61	132	35	28	20	49	30
FamHS	White	USA	2167	8	45	51	127	44	36	12	42	46
CHS	White	USA	1964	9	38	71	133	49	35	4	43	53
YFS	White	Finland	1370	0	43	38	120	9	7	15	47	38
DCH Study‡	White	Denmark	1297	0	45	56	135	47	13	5	32	63
DIOGENES‡ (controls)	White	Denmark	1002	0	51	54	135	38	7	6	36	58
DIOGENES‡ (weight gainers)	White	Denmark	813	0	49	53	135	42	10	5	35	60
PREDIMED-VALENCIA	White	Spain	940	2	36	67	147	84	63	38	46	16
BPRHS	Puerto Rican	USA	845	0	28	57	136	78	56	61	34	5
GOLDN	White	USA	818	0	50	49	118	26	21	10	40	50
Raine	Mixed§	Australia	728	2	48	20	117	4	0	15	39	46
InCHIANTI	White	Italy	647	0	45	64	142	64	49	2	30	68

See web appendix for full titles of studies.

SBP=systolic blood pressure.

^*rs1446585 used as a proxy.

^†rs309137 used as a proxy.

^‡Subsamples from Danish Diet, Cancer and Health cohort.

^§Dominantly white, white-admixed (participants with one or both white parents).