Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Sep 25;9:412. doi: 10.3389/fgene.2018.00412

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Piñero, Gonzalez-Perez, Guney, Aguirre-Plans, Sanz, Oliva and Furlong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Multi-scale network features of the gene sets (INBIOMAP interactomes). We plot the z-score of the network features (degree, P: participation coefficient, Z: within-module degree, BET: betweenness, CC: clustering coefficient) resulting from 10,000 randomizations. The asterisks indicate that the z-score is statically significant (p-value < 0.05). TARGET: drug targets, METAB: proteins that are involved in the drug metabolism, absorption, distribution, metabolism, and excretion. TOXPROT: proteins associated to side effects. TT: genes in common between drug targets and toxicity genes. OT: only TARGET proteins. OTP: only TOXPROT proteins.