Table 3.

Genomic features of the sets of genes.

Gene set	pLI			pNull
	pLI	z-score	p-value	pNull	z-score	p-value
TARGET	0.380	8.87	7.31E-19	0.167	−5.829	5.58E-09
TOXPROT	0.365	10.9	1.15E-27	0.146	−13.604	3.79E-42
METAB	0.214	−4.92	8.65E-07	0.260	3.843	1.22E-04
TT	0.399	7.84	4.51E-15	0.153	−5.607	2.06E-08
OT	0.358	4.15	3.32E-05	0.183	−2.239	0.0251559
OTP	0.354	7.45	9.33E-14	0.143	−12.108	9.58E-34

We show the value of the feature, the z-score resulting from 10,000 randomizations, and its associated two-sided p-value.