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. 2018 Sep 25;9:939. doi: 10.3389/fphar.2018.00939

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Copyright © 2018 Šarenac and Mikov.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Scheme 7 — Regioselective oxidation of CA with an aqueous solution of potassium dichromate in acetic acid in presence of sodium acetate gives the 3α,12α-dihydroxy−7–keto−5β-cholanic acid (Kuhajda et al., 2007).