Figure 1.
Mitral valve prolapse (MVP) with no or moderate regurgitation in patients with (A) Marfan syndrome, (B) myxomatous disease, (C) Filamin-A disease and (D) fibroelastic deficiency (FED). Of note, the echocardiographic presentation of MVP is often similar in Marfan syndrome and myxomatous disease, and Filamin-A MVP can be confused with myxomatous MVP. In addition, myxomatous degeneration of mitral leaflets has been described in Marfan syndrome, myxomatous disease and Filamin-A disease, whereas the histological aspect is quite different in FED. White arrows: prolapse/billowing, black head arrows: mitral annular disjunction.