Figure 3.

Daily alcohol intake (g/kg/24h) shown as mean ±SEM for socially defeated and non-defeated C57BL/6J males with either (A, C, E, G) continuous or (B, D, F, H) intermittent access to alcohol. Mice received systemic doses of (A, B) CP376395, (C, D) metyrapone, (E, F) mifepristone, or (G, H) finasteride prior to the onset of the alcohol access period. For interactions between social defeat stress and drug treatment, significant post-hoc comparisons are depicted as: *p<0.05, **p<0.01 vehicle vs. drug; #p<0.05, ##p<0.01 non-defeated vs. defeated. Best-fit curves are in black. Dark gray lines represent significant post-hoc comparisons in the presence of main effects: *p<0.05, **p<0.01 vehicle vs. drug; #p<0.05, ##p<0.01 non-defeated vs. defeated.