Table 4.

Two- and four-hour intermittent access alcohol intake (g/kg) by socially defeated or non-defeated mice after systemic injections of CP376395, metyrapone, mifepristone or finasteride

		Non-defeated		Socially Defeated
Drug	mg/kg	2hr	4hr	2hr	4hr
CP 376395	veh	3.67 ± 0.26	6.20 ± 0.28	4.72 ± 0.42	7.09 ± 0.60
	10a	3.65 ± 0.72	6.44 ± 0.75	3.03 ± 0.55	5.19 ± 0.58
	17ab	1.65 ± 0.38	4.42 ± 1.02	2.37 ± 0.33	4.21 ± 0.50
	30ab	1.38 ± 0.31	2.27 ± 0.55	1.19 ± 0.26	3.22 ± 0.59
Metyraponecd	veh	2.41 ± 0.35	3.95 ± 0.47	3.65 ± 0.23	5.24 ± 0.45
	10	2.27 ± 0.32	3.44 ± 0.53	3.73 ± 0.27	5.36 ± 0.44
	30	2.42 ± 0.36	3.63 ± 0.70	3.10 ± 0.43	4.58 ± 0.47
	50ab	1.58 ± 0.37	1.80 ± 0.42	2.21 ± 0.28	3.66 ± 0.27
Mifepristonecd	veh	1.78 ± 0.29	4.17 ± 0.68	2.61 ± 0.28	5.20 ± 0.71
	17	1.71 ± 0.34	5.19 ± 0.81	2.43 ± 0.36	4.73 ± 0.93
	30	1.55 ± 0.28	2.92 ± 0.53	2.18 ± 0.29	4.99 ± 0.59
	56	1.40 ± 0.33	3.36 ± 0.66	1.68 ± 0.42	4.10 ± 0.77
	100	1.40 ± 0.20	3.02 ± 0.37	2.46 ± 0.23	4.56 ± 0.49
Finasteridecd	veh	1.66 ± 0.38	3.46 ± 0.85	2.75 ± 0.39	6.06 ± 0.68
	10	1.88 ± 0.41	4.11 ± 0.66	2.19 ± 0.45	5.17 ± 0.84
	30ab	0.50 ± 0.16	1.94 ± 0.46	1.84 ± 0.48	4.58 ± 0.99
	100ab	0.29 ± 0.20	0.97 ± 0.32	0.58 ± 0.38	2.21 ± 0.58

Mean ± SEM; main effects of drug followed by post-hoc comparisons of vehicle vs. drug dose:

^ap <0.05 at 2hr,

^bp <0.05 at 4hr; main effects of social stress followed by post-hoc comparisons of socially defeated vs. non-defeated:

^cp <0.05 at 2hr,

^dp <0.05 at 4hr