Table 4. Structural volumes.

Structural Volumes (cm3)	HoM	HeM	HeW	P and F(df) values
L caudate	4.2±0.5	4.2±0.5	3.9±0.4	p = .031 F = 6.2(2,100)
R caudate	4.2±0.5	4.2±0.5	4.0±0.4	p = .002 F = 6.8(2,100)
L putamen	5.3±0.5	5.4±0.7	4.8±0.6	p = .400 F = 0.9(2,100)
R putamen	5.2±0.5	5.2±0.6	4.7±0.6	p = .401 F = 0.8(2,100)
L hippocampus	4.2±0.5	4.3±0.4	3.9±0.4	p = .026 F = 3.8(2,100)
R hippocampus	4.2±0.6	4.4±0.6	4.1±0.3	p = .003 F = 6.0(2,100)
L amygdala	2.0±0.2	2.0±0.2	1.7±0.2	p = .400 F = 0.7(2,100)
R amygdala	2.1±0.3	2.0±0.3	1.8±0.2	p = .480 F = 0.8 (2,100)
L thalamus	7.1±0.4	7.4±0.6	6.8±0.6	p = .002 F = 6.4(2,100)
R thalamus	7.2 ±0.7	7.5±0.7	6.7±0.6	p = .043 F = 3.2(2,100)
TIV	1625.5±123.0	1638.4±129.3	1426.5±117.7	p = .0001 F = 37.95(2,100)

TIV = total intracranial volume; P-values for structural volumes were based on calculations of ratios between the respective structural volume and the TIV.

HeW had smaller TIV than both male groups; There was no difference between HeM and HoM in TIV. Right caudate volume/TIV was larger in HeW compared to HeM, p = .001 and HoM, p = .020; The corresponding p-values for the left caudate/TIV were .003 and .018. The right hippocampus volume/TIV was larger in HeW than HeM (p = .007), and HoM (p = .007). For the left hippocampus/TIV the corresponding p-values were .036 and p = .063. There was no significant difference between HeM and HoM in the caudate/TIV or hippocampus/TIV. The left thalamus volume/TIV was smaller in HoM compared to HeW (p = .003) but not to HeM (p = .053). The corresponding p-values for the right thalamus volume/TIV were .044 and .420. No significant difference was detected between the two control groups in the thalamus volumes.