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. 2018 Aug 14;59(10):1880–1892. doi: 10.1194/jlr.M085431

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Copyright © 2018 Madsen et al. Published by The American Society for Biochemistry and Molecular Biology, Inc.

Author’s Choice—Final version open access under the terms of the Creative Commons CC-BY license.

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Fig. 6. — Incorporation of labeled choline into PC molecular species of the mouse lung (A, B, C, and F) and BALF (D, E, and G). Incorporation of [5¹³C]choline derived from the hydrolysis of [U¹³C]DPPC is shown for the enrichments of total [5¹³C]PC species in the lungs (A), individual [5¹³C]PC species in the lungs from CHF5633- (B) and poractant alfa-treated mice (C), and individual [5¹³C]PC species in BALF from CHD5633- (D) and poractant alfa-treated mice (E). Results were normalized for the enrichment of [U¹³C]DPPC in administered surfactant to enable a direct comparison between CHF5633- and poractant alfa-treated mice. The incorporation of methyl-D₉-choline is shown in F and G for the lungs and BALF for CHF5633-treated mice. Results are presented as means ± SEMs.