Fig. 1.

The effect of Ang II on the expression of ABCA1. The abundance of ABCA1 protein (A) and mRNA (B) in INS-1 cells treated with varying concentrations (0, 10, 100, and 1,000 nM) of Ang II. C, D: The effect of Ang II at a concentration of 10 nM on the protein (C) and mRNA (D) expression of ABCA1 in rat pancreatic islets. The ratio of ABCA1 to GAPDH is shown as percent of control. A graph showing the mean ± SEM (n = 3) of separate experiments for each treatment group is included. * P < 0.05 compared with 0.