TABLE 2.

Comparison of the FA saturation levels within the selected lipid classes between CTRL, NAFL, and NASH groups

	CTRL	NAFL	NASH
TG
SFA	40.3 ± 0.66	41.4 ± 1.11	43.1 ± 0.50a
MUFA	48.8 ± 0.57	48.3 ± 0.48	47.7 ± 0.42
DUFA	10.7 ± 0.62	10.2 ± 0.74	9.1 ± 0.37
PUFA	0.20 ± 0.02	0.16 ± 0.02	0.14 ± 0.01a
DG
SFA	39.4 ± 0.89	36.0 ± 1.47b	36.5 ± 0.92
MUFA	38.5 ± 1.70	47.5 ± 1.26a	50.1 ± 1.00c
DUFA	12.0 ± 0.64	10.1 ± 0.86	9.10 ± 0.48a
PUFA	10.0 ± 0.84	6.38 ± 0.66b	4.36 ± 0.17c,d
CE
SFA	35.2 ± 0.69	32.8 ± 0.83	29.7 ± 0.60c,d
MUFA	25.1 ± 0.91	22.7 ± 0.92	21.8 ± 0.80b
DUFA	32.3 ± 1.08	35.9 ± 1.06	38.9 ± 1.11a
PUFA	7.32 ± 0.49	8.61 ± 0.56	9.59 ± 0.36a
Cardiolipin
SFA	0.26 ± 0.05	0.38 ± 0.16	0.41 ± 0.08
MUFA	11.5 ± 0.44	12.8 ± 1.55	12.8 ± 0.36b
DUFA	87.4 ± 0.47	86.0 ± 1.70	86.0 ± 0.38b
PUFA	0.83 ± 0.08	0.76 ± 0.07	0.81 ± 0.06
Acylcarnitine
SFA	62.7 ± 3.65	52.3 ± 4.69	57.9 ± 2.63
MUFA	25.0 ± 3.68	32.0 ± 3.97	36.0 ± 2.45b
DUFA	12.3 ± 2.58	15.7 ± 4.85	6.19 ± 0.88
PUFA	—	—	—

Data in each lipid class are shown as mean ± SEM and were analyzed with the Kruskal-Wallis test and corrected for multiple comparisons with the Benjamini-Hochberg approach. The Mann-Whitney U test corrected with the Dunn-Sidak approach was the post hoc analysis (n = 16 for CTRL; n = 10 for NAFL; n = 32 for NASH).

^aP < 0.01 versus CTRL.

^bP < 0.05 versus CTRL.

^cP < 0.001 versus CTRL.

^dP < 0.05 versus NAFL.