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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Dig Liver Dis. 2018 Apr 23;50(10):1068–1075. doi: 10.1016/j.dld.2018.04.009

Figure 1. The effects of hepatic FXR deficiency and alcohol treatment on liver weight (LW), body weight (BW) and serum parameters.

Figure 1

(A) Relative LW/BW ratio (left) and BW gain after alcohol feeding. The values represent the percent changes in BW compared to the starting BW (right). (B) Serum activities of ALT and ALP and serum levels of BAs, TG and TC in mice after being fed with isocaloric vehicle or Lieber-DeCarli alcohol-containing diet (5% v/v). Data are expressed as mean ± SD. * indicates significant difference (p<0.05) between different genotypes (WT vs FXRhep−/−); # indicates significant difference (p<0.05) between treatments (Veh vs EtOH).