Table 1.

Experimental animal models of human helminth infections

Animal model	Human infection mimicked	Form of Transmission	Route of administration	Affected compartment
Nippostrongylus brasiliensis	Ascaris lumbricoides Ancylostoma duodenale Necator americanus	Larvae	Subcutaneous	Skin, Lungs, Intestinal Tract
Heligmosomoides polygyrus		Larvae	Oral	Intestinal Tract
Strongyloides venezuelensis	Strongyloides stercoralis	Larvae	Subcutaneous	Skin, Lungs, Intestinal Tract
Trichuris muris	Trichuris trichiura	Egg	Oral	Intestinal Tract
Trichinella spiralis	Trichinella spiralis	Larvae	Oral	Intestinal Tract, Skeletal Muscle
Schistosoma mansoni	Schistosoma spp.	Cercariae	Percutaneous Exposure Subcutaneous	Skin, Liver, Lungs
Brugia malayi	Lymphatic filariasis	Larvae	Subcutaneous	Blood, Pleural cavity