Table 2. Clinical and Demographic Data for IL-5 low/high and IL-13 low/high CRS.
Data is presented as frequencies (percentages) means +/− standard deviation or medians with intraquartile range.
| IL-5-low CRS | IL-5-high CRS | p-value | IL-13-low CRS | IL-13-high CRS | p-value | |
|---|---|---|---|---|---|---|
| No. | 40 | 50 | 74 | 16 | ||
| Age (years) | 50.2 +/− 12.0 | 47.1 +/− 13.9 | 0.27 | 48.1 +/− 13.0 | 49.9 +/− 14.2 | 0.64 |
| Sex, no. (% female) | 21 (53) | 21 (42) | 0.40 | 38 (51) | 4 (25) | 0.10 |
| Nasal polyps, no. (%) | 10 (25) | 43 (86) | <0.0001 | 39 (53) | 14 (88) | 0.01 |
| Asthma, no. (%) | 12(30) | 30 (60) | 0.006 | 29 (38) | 13 (81) | 0.005 |
| Allergic Rhinitis, no. (%) | 21 (50) | 35 (70) | 0.13 | 46 (61) | 10 (63) | 1.00 |
| AERD, no. (%) | 0 (0) | 12 (24) | 0.001 | 6 (8) | 6 (38) | 0.006 |
| AFRS, no. (%) | 1 (3) | 9 (18) | 0.04 | 3 (4) | 7 (44) | 0.0001 |
| SNOT-22 score | 48.9 +/− 16.7 | 45.7 +/− 20.2 | 0.55 | 44.4 +/− 17.3 | 58.9 +/− 20.6 | 0.03 |
| CT score | 13.5 (10.0-17.0) | 17.3 (13.0-22.0) | 0.0003 | 14.5 (11.0-17.6) | 20.8 (10.0-22.2) | <0.0001 |
| SIT score | −4 (−8 - -1) | −20.5 (−27.8 - -7.0) | <0.0001 | −5.0(−20.9–2.0) | −21.5(−29.5–16.0) | 0.001 |
| Prior surgery, no. (%) | 12 (30) | 29 (58) | 0.01 | 31 (42) | 11 (69) | 0.06 |
| # of prior surgeries | 0.48 +/− 0.96 | 1.08 +/− 1.32 | 0.02 | 0.68 +/− 1.05 | 1.38 +/− 1.59 | 0.03 |
| Tissue eosinophils/HPF | 3.5 (0-29.5) | 56.0 (24.5-100.0) | <0.0001 | 25.0 (1.0-85.0) | 61.5 (33.5-156.3) | 0.01 |
AERD, aspirin-exacerbated respiratory disease; AFRS, allergic fungal rhinosinusitis; CT, computed tomography; SIT, smell identification test; SNOT-22, sinonasal outcome test-22; HPF, high power field. Bold, p<0.05.