Table 3. Clinical and Demographic Data for IL-5 low/high and IL-13 low/high CRSwNP.
Data is presented as frequencies (percentages) means +/− standard deviation or medians with intraquartile range.
| IL-5-low CRSwNP | IL-5-high CRSwNP | p-value | IL-13-low CRSwNP | IL-13-high CRSwNP | p-value | |
|---|---|---|---|---|---|---|
| No. | 10 | 43 | 39 | 14 | ||
| Age (years) | 52.6 +/− 11.3 | 48.1 +/− 13.5 | 0.34 | 48.2 +/− 12.8 | 51.4 +/− 14.3 | 0.44 |
| Sex, no. (% female) | 4 (40) | 17 (40) | 1.00 | 18 (46) | 3 (21) | 0.13 |
| Asthma, no. (%) | 4 (40) | 27 (63) | 0.29 | 19 (49) | 12 (86) | 0.03 |
| Allergic Rhinitis, no. (%) | 6 (60) | 30 (70) | 0.71 | 27 (69) | 9 (64) | 0.75 |
| AERD, no. (%) | 0 (0) | 12 (28) | 0.09 | 6 (15) | 6 (43) | 0.06 |
| AFRS, no. (%) | 1 (20) | 9 (21) | 0.67 | 3 (10) | 7 (50) | 0.002 |
| SNOT-22 score | 52.5 +/− 19.5 | 44.5 +/− 20.7 | 0.40 | 42.2 +/− 18.8 | 57.1 +/− 22.1 | 0.07 |
| CT score | 17.0 (13.5-18.8) | 15.5 (9.0-18.0) | 0.28 | 16.5 (13.0-20.0) | 22.8 (20.8-24.0) | <0.0001 |
| SIT score | −6.5(−17.3–4.3) | −24.0(−28.0–8.0) | 0.03 | −11.5(−25.9–4.3) | −28.0(−30–20) | 0.005 |
| Prior surgery, no. (%) | 4 (40) | 27 (63) | 0.54 | 22 (56) | 9 (64) | 0.76 |
| # of prior surgeries | 0.50 +/− 0.71 | 1.16 +/− 1.34 | 0.14 | 0.90 +/− 1.07 | 1.43 +/− 1.70 | 0.18 |
| Tissue eosinophils/HPF | 14.5 (0.8-35.0) | 73.0 (35.0-100.0) | 0.002 | 50.0 (15.0-100.0) | 74.0(50.0-177.5) | 0.10 |
AERD, aspirin-exacerbated respiratory disease; AFRS, allergic fungal rhinosinusitis; CT, computed tomography; SIT, smell identification test; SNOT-22, sinonasal outcome test-22; HPF, high power field. Bold, p<0.05.