Table 4. Clinical and Demographic Data for Th2 low/high CRS (A) and Th2 low/hogh CRSwNP (B).
Data is presented as frequencies (percentages) means +/− standard deviation or medians with intraquartile range.
| Th2-low CRS | Th2-high CRS | p-value | Th2-low CRSwNP | Th2-high CRSwNP | p-value | |
|---|---|---|---|---|---|---|
| No. | 49 | 41 | 15 | 38 | ||
| Age (years) | 48.8 +/− 12.3 | 48.1 +/− 12.1 | 0.79 | 48.3 +/− 11.2 | 49.3 +/− 13.9 | 0.82 |
| Sex, no. (% female) | 27 (55) | 15 (37) | 0.09 | 7 | 14 | 0.55 |
| Nasal polyps, no. (%) | 15 (31) | 38 (93) | <0.0001 | - | - | - |
| Asthma, no. (%) | 16 (33) | 25 (61) | 0.06 | 7 (47) | 24 (63) | 0.36 |
| Allergic Rhinitis, no. (%) | 26 (53) | 29 (71) | 0.20 | 9 (60) | 27 (71) | 0.52 |
| AERD, no. (%) | 1 (2) | 11 (27) | 0.002 | 1 (7) | 11 (29) | 0.14 |
| AFRS, no. (%) | 1 (4) | 9 (22) | 0.07 | 1 (13) | 9 (24) | 0.25 |
| SNOT-22 score | 47.8 +/−15.9 | 44.5 +/− 20.2 | 0.50 | 50.0 +/− 17.1 | 44.7 +/− 21.6 | 0.54 |
| CT score | 14.0 (10.0-17.0) | 18.0 (14.3-22.3) | <0.0001 | 16.0 (13.0-18.0) | 20.0 (15.9-22.6) | 0.07 |
| SIT score | −4.0(−8.8–1.3) | −21.0(−28.0–7.0) | 0.0002 | −8.0(−25.0–5.0) | −23.8(−28.0–9.0) | 0.21 |
| Prior surgery, no. (%) | 17 | 25 | 0.02 | 7 (47) | 24 (63) | 0.36 |
| # of prior surgeries | 0.55 +/− 0.96 | 1.10 +/− 1.36 | 0.01 | 0.73 +/− 0.88 | 1.16 +/− 1.39 | 0.37 |
| Tissue eosinophils/HPF | 4.5 (1.0-35.0) | 67.0 (29.0-120.0) | <0.0001 | 25.0 (1.0-50.0) | 74.0 (46.9-142.5) | 0.002 |
AERD, aspirin-exacerbated respiratory disease; AFRS, allergic fungal rhinosinusitis; CT, computed tomography; SIT, smell identification test; SNOT-22, sinonasal outcome test-22; HPF, high power field. Bold, p<0.05.