Table 1.
Treatment (mg/kg) | Cardiac damage score CDS 6 hearts/group × 6 slices/heart | ± S.D. | ||||
---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 4 | ||
Control | 36 | 0 | 0 | 0 | 0 | 0.00 ± 0.00 |
LPS | 0 | 0 | 0 | 19 | 17 | 3.87 ± 0.54 a3 |
Simvastatin 10 + LPS | 0 | 0 | 18 | 18 | 0 | 2.80 ± 0.48 a1 |
Simvastatin 20 + LPS | 0 | 6 | 21 | 9 | 0 | 2.08 ± 0.65 a1b2 |
Simvastatin 40 + LPS | 0 | 20 | 16 | 0 | 0 | 1.44 ± 0.43 b2 |
Statistical analysis was performed using Kruskal Wallis test. a1, a3 - p < 0.05, 0.001 for the results compared with the control group, b2 - p < 0.01 for the results compared with LPS group.