Table 2.
Types of ‘Levodopa Phobia’ types and possible motor and non-motor complications
| Types of ‘Levodopa Phobia’ | Patterns of complications and clinical consequences |
|---|---|
| Complete ‘Levodopa Phobia’ | Severe akinesia causing lack of mobility |
| Contractures | |
| Respiratory tract infections | |
| Severe nociceptive pain | |
| Depression and anhedonia | |
| Social withdrawal and carer dependence | |
| Poor compliance and secret rejection of levodopa use | Report of lack of any effect of levodopa inspite of apparent use |
| Precipitation of unnecessary investigations for atypical ‘levodopa-resistant’ parkinsonism | |
| A tendency to seek multiple medical consultations owing to ‘lack of effect’ of therapy | |
| Possibility of development of impulse control disorders because of potential overuse of other (e.g., dopamine agonist) therapies |