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. 2018 Oct 2;4:31. doi: 10.1038/s41531-018-0067-z

Table 2.

Types of ‘Levodopa Phobia’ types and possible motor and non-motor complications

Types of ‘Levodopa Phobia’ Patterns of complications and clinical consequences
Complete ‘Levodopa Phobia’ Severe akinesia causing lack of mobility
Contractures
Respiratory tract infections
Severe nociceptive pain
Depression and anhedonia
Social withdrawal and carer dependence
Poor compliance and secret rejection of levodopa use Report of lack of any effect of levodopa inspite of apparent use
Precipitation of unnecessary investigations for atypical ‘levodopa-resistant’ parkinsonism
A tendency to seek multiple medical consultations owing to ‘lack of effect’ of therapy
Possibility of development of impulse control disorders because of potential overuse of other (e.g., dopamine agonist) therapies