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. 2018 Oct 2;8:14695. doi: 10.1038/s41598-018-32720-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Biopotential readings correlate with tumour stage and poor progression free survival. (a) Biopotential readings of all advanced ovarian cancer cases at Stage III (n = 18) and Stage IV (n = 18) shows that higher biopotential levels associate with late stage. The p-value was determined by Welch two Sample t-test (p = 0.0487). (b) Kaplan-Meier plot representing the biopotential association with PFS in ovarian cancer cases of all subtypes (n = 31). (c) Biopotential association with PFS in high grade serous ovarian cancer (n = 27). In both Kaplan-Meier analysis, the patients were dichotomised at median biopotential and formed the biopotential high group (red) and the biopotential low group (blue). Within the cohort of patients with biopotential below the median, it was a 2:1 ratio of patients with Stage III versus Stage IV EOC disease. The p-value was given by log-rank test. Additionally, hazard ratio (HR), 95% confidence interval and the corresponding p-value was given by Cox regression.