Fig. 3.

Variant concordance and Mendelian error (ME) rates were calculated for different variant classes and genomic regions using 100 samples, including 8 trios from the 1000 Genomes Project and 19 quads from the Simons Simplex Collection. a Variant concordance rates were calculated from pairwise comparisons across five pipelines for 100 samples. b Mendelian error rates were calculated using informative sites in 44 parent-offspring trios, for variants classified as concordant and discordant in pairwise comparisons between five pipelines. The center line is the median, the upper and lower hinges are the first and third quartiles, and the whiskers extend to the largest/smallest values no further than 1.5 * inter-quartile range from the hinge