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. 2018 Sep 26;9:546. doi: 10.3389/fendo.2018.00546

Table 1.

Pre-pregnancy obesity-related risks to women and offspring.

Period Women Offspring
Before conception Menstrual cycle dysregulation, anovulation and infertility (11)
Pregnancy Miscarriage (12)
Gestational diabetes mellitus (13)
Pregnancy-induced hypertension (14, 15)
Preeclampsia (16)
Thrombo-embolism (17)
Congenital defects (18, 19)
Premature birth (20)
Large for gestational age Macrosomia (>4,000 g) (21)
Delivery Cesarean sections Labor induction, surgical complications and failures of epidural analgesia (3, 2226) Stillbirth (24, 27) Neonatal trauma (assisted vaginal delivery and head trauma, shoulder dystocia) (7, 28)
Low umbilical arterial pH < 7.1 and low Apgar score at 5 and 10 min (7)
Postpartum Difficulties in initiating and sustaining breastfeeding (29) Systematic transfer to monitoring in case of GDM (risk of hypoglycemia) (7)
Increased admission rate in the intensive care unit (30)
Long-term Postpartum weight retention and inter-pregnancy obesity (31, 32)
Type 2 diabetes Long-term vascular dysfunction (14, 15)
Childhood obesity and premature metabolic syndrome (33)
Premature death from cardiovascular disease (22)