Table 1.
Period | Women | Offspring |
---|---|---|
Before conception | Menstrual cycle dysregulation, anovulation and infertility (11) | – |
Pregnancy | Miscarriage (12) Gestational diabetes mellitus (13) Pregnancy-induced hypertension (14, 15) Preeclampsia (16) Thrombo-embolism (17) |
Congenital defects (18, 19) Premature birth (20) Large for gestational age Macrosomia (>4,000 g) (21) |
Delivery | Cesarean sections Labor induction, surgical complications and failures of epidural analgesia (3, 22–26) | Stillbirth (24, 27) Neonatal trauma (assisted vaginal delivery and head trauma, shoulder dystocia) (7, 28) Low umbilical arterial pH < 7.1 and low Apgar score at 5 and 10 min (7) |
Postpartum | Difficulties in initiating and sustaining breastfeeding (29) | Systematic transfer to monitoring in case of GDM (risk of hypoglycemia) (7) Increased admission rate in the intensive care unit (30) |
Long-term | Postpartum weight retention and inter-pregnancy obesity (31, 32) Type 2 diabetes Long-term vascular dysfunction (14, 15) |
Childhood obesity and premature metabolic syndrome (33) Premature death from cardiovascular disease (22) |