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. 2018 Sep 26;9:1205. doi: 10.3389/fphys.2018.01205

Table 1.

Gene clusters whose expression was more than 1.4 times higher or lower than that in the control group, following treatment with the AM18W-13a extract for 1 h.

Upregulated genes
Gene symbol Gene name Ratio
1 h 24 h
Vapb Vesicle-associated membrane protein, associated protein B and C 1.88 1.28
Rgs1 Regulator of G-protein signaling 1 1.70 0.51
Egr3 Early growth response 3 1.53 1.09
Naa35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 1.56 0.90
Egr2 Early growth response 2 1.55 1.05
Zfp146 Zinc finger protein 146 1.49 1.02

Downregulated genes
Gene symbol Gene title Ratio
1 h 24 h

Ndufs8 NADH dehydrogenase (ubiquinone) Fe-S protein 8 0.51 1.02
Cxcl2 Chemokine (C-X-C motif) ligand 2 0.52 0.58
Nfkbiz Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, ze 0.60 1.12
Ppm1b Protein phosphatase 1B, magnesium dependent, beta isoform 0.61 0.87
Hnrnpab Heterogeneous nuclear ribonucleoprotein A/B 0.62 1.29
Pde4b Phosphodiesterase 4B, cAMP specific 0.66 1.15
Traf1 TNF receptor-associated factor 1 0.68 0.94
Nfkbie Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, ep 0.69 1.04
Ier3 Immediate early response 3 0.70 0.64

The values indicate the average of results obtained from independent experiments performed in duplicate or triplicate.