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5-Fluorouracil and capecitabine metabolism in liver and tumor cells. CD indicates cytidine deaminase; CE, carboxyl esterase; 5′-DFCR, 5′-deoxy-5-fluorocytidine; 5′-DFUR, 5′-deoxy-5-fluorouridine; DHFU, dihydro-5-fluorouracil; DPD, dihydropyrimidine dehydrogenase; 5FU, fluorouracil; TP, thymidine phosphorylase.
