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Exhaled nitric oxide fraction (FeNO) algorithm
| FeNO concentration ppb | ICS dose change | ACQ score | β2-agonist dose change | |
| Level 1 | >29 | ↑ 1 ICS step | ≤1.5 | No change |
| Level 2 | 16–29 | No change | >1.5 | ↑ 1 LABA step |
| Level 3 | <16 | ↓ 1 ICS step | NA (FeNO >29 ppb) | No change |
ICS: inhaled corticosteroid; ACQ: Asthma Control Questionnaire; LABA: long-acting β2-agonist; NA: not applicable.
