Figure 2.
The effects of crocin treatment on joint inflammation, bone erosion and cartilage destruction in CIA rats. The ankle joints were subjected to histological analysis and inflammation (A), chondrocyte death (B), cartilage surface erosion (C), bone erosion (D) on day 36 after crocin treatment. Norm: normal rats; Cont: control CIA rats. Data are presented as the mean ± SE (n = 15). *p < 0.05, **p < 0.01, compared with the Cont.