Table 1.
Baseline Demographics and Clinical Characteristics of the Analysis Population (n = 79)
| Characteristic | Mean (SD) |
|---|---|
| Age, y | 53.41 (11.63) |
| Serum albumin level, g/L | 23.95 (3.51) |
| Days since admission | 1.81 (0.88) |
| MELD | 20.90 (6.62) |
| Creatinine level | 91.2 (78.2) |
| n (%) | |
| Male | 52 (66) |
| Admitted to ICU | 2 (3) |
| Prescribed antibiotics | 41 (52) |
| Diagnosis of infection | 27 (34) |
| Etiology of cirrhosisa | |
| Alcohol | 76 (96) |
| Hepatitis B | 1 (1) |
| Hepatitis C | 11 (14) |
| NAFLD | 4 (5) |
| Other etiologies | 2 (3) |
| Organ dysfunctionb | |
| Renal | 8 (10) |
| Respiratory | 9 (11) |
| Circulatory | 13 (16) |
| Cerebral | 3 (4) |
| ACLF gradec | |
| Grade 0 | 58 (73) |
| Grade 1 | 11 (14) |
| Grade 2 | 6 (8) |
| Grade 3 | 4 (5) |
ACLF, acute-on-chronic liver failure; ICU, intensive care unit; MELD, Model for End-stage Liver Disease; NAFLD, nonalcoholic fatty liver disease.
a
Some patients have more than 1 cirrhosis etiology.
b
Organ dysfunction at baseline was determined according to the following criteria: renal, creatinine level > 133 μmol/L; respiratory, oxygen saturations divided by inspired oxygen < 357; circulatory, mean arterial pressure < 60 mm Hg or patient is receiving inotropic/vasopressor support; cerebral, grade III or IV encephalopathy.
c
According to European Association for the Study of the Liver-CLIF criteria.