Table 3.
Baseline clinical and health related characteristics of participants from Women’s Health Initiative Observational Study and Women’s Health Initiative Clinical Trials included in analytic sample* in study of effect of postmenopausal weight change on risk of fracture. Figures are numbers (percentage) of participants
| Variable | Stable weight (n=79 279) | Weight loss (n=18 266) | Weight gain (n=23 021) | Total |
|---|---|---|---|---|
| Daily oral corticosteroid use: | ||||
| No | 77 889 (98) | 17 743 (97) | 22 531 (98) | 118 163 (98) |
| Yes | 1390 (2) | 523 (3) | 490 (2) | 2403 (2) |
| Total | 79 279 | 18 266 | 23 021 | 120 566 |
| Dietary+supplemental calcium (mg/day): | ||||
| <800 | 26 648 (34) | 6359 (35) | 8123 (35) | 41 130 (34) |
| 800-<1200 | 19 670 (25) | 4535 (25) | 5516 (24) | 29 721 (25) |
| ≥1200 | 32 961 (42) | 7372 (40) | 9382 (41) | 49 715 (41) |
| Total | 79 279 | 18 266 | 23 021 | 120 566 |
| Dietary+supplemental vitamin D (IU/day): | ||||
| <200 | 29 223 (37) | 6879 (38) | 8735 (38) | 44 837 (37) |
| 200-<400 | 14 906 (19) | 3459 (19) | 3994 (17) | 22 359 (19) |
| 400-<600 | 19 563 (25) | 4486 (25) | 5873 (26) | 29 922 (29) |
| ≥600 | 15 587 (20) | 3442 (19) | 4419 (19) | 23 448 (20) |
| Total | 79 279 | 18 266 | 23 021 | 120 566 |
| Arthritis: | ||||
| Rheumatoid arthritis | 3504 (4) | 972 (5) | 1053 (5) | 115 037 (95) |
| Other/don’t know | 75 775 (96) | 17 294 (95) | 21 968 (95) | 5529 (5) |
| Total | 79 279 | 18 266 | 23 021 | 120 566 |
| Diabetes treatment (oral or injectable) (missing=95): | ||||
| No | 76 457 (97) | 17 266 (95) | 22 109 (96) | 115 832 (96) |
| Yes | 2756 (3) | 987 (5) | 896 (4) | 4639 (4) |
| Total | 79 213 | 18 253 | 23 005 | 120 471 |
| Bilateral oophorectomy (missing=2594): | ||||
| No | 62 361 (80) | 14 240 (80) | 18 170 (81) | 94 771 (80) |
| Yes | 15 264 (20) | 3583 (20) | 4354 (19) | 23 201 (20) |
| Total | 77 625 | 17 823 | 22 524 | 117 972 |
| Hysterectomy (missing=52): | ||||
| No | 46 539 (59) | 10 678 (58) | 13 483 (59) | 70 700 (59) |
| Yes | 32 699 (41) | 7583 (42) | 9532 (41) | 49 814 (41) |
| Total | 79 238 | 18 261 | 23 015 | 120 514 |
| Menopausal hormone therapy use (missing=88): | ||||
| Never used | 33 992 (43) | 8420 (46) | 9451 (41) | 51 863 (43) |
| Past user | 12 757 (16) | 2995 (16) | 3644 (16) | 19 396 (16) |
| Current user | 32 472 (41) | 6838 (37) | 9909 (43) | 49 219 (41) |
| Total | 79 221 | 18 253 | 23 004 | 120 478 |
| Self rated general health status (missing=663): | ||||
| Excellent | 14 639 (19) | 2618 (14) | 4109 (18) | 21 366 (18) |
| Very good | 34 123 (43) | 7272 (40) | 9570 (42) | 50 965 (42) |
| Good | 24 667 (31) | 6470 (36) | 7310 (32) | 38 447 (32) |
| Fair | 5104 (6) | 1629 (9) | 1746 (8) | 8479 (7) |
| Poor | 323 (0) | 159 (1) | 164 (1) | 646 (1) |
| Total | 78 856 | 18 148 | 22 899 | 119 903 |
| No of falls in past 12 months (missing=5271): | ||||
| None | 51 686 (68) | 11 334 (65) | 14 753 (67) | 77 773 (67) |
| 1 | 15 255 (20) | 3608 (21) | 4448 (20) | 23 311 (21) |
| 2 | 6046 (8) | 1567 (9) | 1886 (9) | 9499 (8) |
| ≥3 | 2886 (4) | 827 (5) | 999 (5) | 4712 (4) |
| Total | 75 873 | 17 336 | 22 086 | 115 295 |
*All P<0.001 for differences between weight groups.