Table 3.
Cox Proportional Hazard Survival Analysis for New-Onset Self-reported Periodontal Disease.
| No FamHxMI | FamHxMI | |||
|---|---|---|---|---|
| Model 1 | Reference | 1.18 (1.01 to 1.38) | ||
| Model 2 | Reference | 1.18 (1.01 to 1.37) | ||
| Model 3 | Reference | 1.16 (1.00 to 1.36) | ||
| Nonsmoker |
Smoker |
|||
| Group 1: No FamHxMI | Group 2: FamHxMI | Group 3: No FamHxMI | Group 4: FamHxMI | |
| Model 1a | Reference | 1.23 (0.98 to 1.54) | 1.35 (1.20 to 1.52) | 1.52 (1.23 to 1.89) |
| Model 2a | Reference | 1.23 (0.98 to 1.54) | 1.35 (1.20 to 1.52) | 1.52 (1.23 to 1.89) |
| Model 3a | Reference | 1.22 (0.97 to 1.53) | 1.33 (1.18 to 1.49) | 1.48 (1.19 to 1.84) |
Values are presented as hazard ratio (95% CI). Bold indicates P < 0.05 (Cox proportional hazard model). All covariates in Model 1 to 3 were reported at the study baseline except for incident diabetes, which was recorded time varying by annual follow-up questionnaires and verified with medical records. Model 1: adjusted for age, education, income, BMI, smoking. Model 2 (time varying) = adjusted for age, education, income, BMI, smoking, incident DM, HRT. Model 3 (time varying) = adjusted for age, education, income, BMI, smoking, incident DM, HRT, standardized serum levels of 1-SD increase of HDL, LDL, ICAM, fibrinogen, and CRP.
BMI, body mass index; CRP, C-reactive protein (natural logarithm transformed); DM, diabetes; FamHxMI, family history of myocardial infarction; HDL, high-density lipoprotein; HRT, hormone replacement therapy; ICAM, intercellular adhesion molecule 1; LDL, low-density lipoprotein.
Same as Models 1 to 3 but without smoking.