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. 2018 Jun 21;97(10):1106–1113. doi: 10.1177/0022034518782189

Table 4.

Risks of Ever Having Periodontal Disease by Inflammatory Biomarkers versus FamHxMI and Smoking Status.

RFInteraction
Group 2: FamHxMI, Nonsmoker Group 3: No FamHxMI, Smoker Group 4: FamHxMI, Smoker
RF RFMain Effect Group 3 Group 4
Bachelor degree 1.08 (0.97 to 1.20) 1.09 (0.94 to 1.26) 1.07 (0.82 to 1.39) 1.14 (0.93 to 1.39) 1.87 (1.70 to 2.06) 2.06 (1.73 to 2.44)
Income 1.00 (0.96 to 1.04) 0.99 (0.93 to 1.04) 0.98 (0.89 to 1.08) 1.10 (0.65 to 1.81) 2.06 (1.62 to 2.61) 2.30 (1.47 to 3.58)
BMI 1.01 (1.00 to 1.02) 1.00 (0.98 to 1.01) 0.98 (0.96 to 1.00) 1.83 (1.07 to 3.09) 2.17 (1.63 to 2.91) 3.75 (2.16 to 6.50)
HRT 1.10 (0.99 to 1.22) 0.93 (0.81 to 1.07) 1.06 (0.82 to 1.38) 1.31 (1.08 to 1.59) 1.99 (1.81 to 2.20) 2.05 (1.72 to 2.44)
Incident DM 1.31 (1.06 to 1.63) 0.84 (0.63 to 1.12) 0.55 (0.32 to 0.91) 1.19 (1.02 to 1.38) 1.95 (1.81 to 2.10) 2.19 (1.92 to 2.51)
HDLa 0.98 (0.92 to 1.03) 0.97 (0.91 to 1.05) 1.08 (0.95 to 1.23) 1.17 (1.01 to 1.35) 1.93 (1.80 to 2.07) 2.12 (1.86 to 2.41)
LDLa 1.12 (1.06 to 1.18) 1.01 (0.94 to 1.08) 0.98 (0.86 to 1.11) 1.17 (1.01 to 1.36) 1.93 (1.80 to 2.07) 2.09 (1.83 to 2.38)
CRPa 1.10 (1.04 to 1.16) 0.93 (0.87 to 1.00) 0.83 (0.73 to 0.95) 1.18 (1.01 to 1.36) 1.93 (1.80 to 2.07) 2.12 (1.86 to 2.41)
ICAMa 1.06 (0.99 to 1.12) 1.08 (1.01 to 1.17) 1.10 (0.97 to 1.25) 1.16 (1.00 to 1.35) 1.87 (1.74 to 2.01) 2.04 (1.79 to 2.33)
Fibrinogena 1.13 (1.07 to 1.19) 0.97 (0.91 to 1.04) 0.88 (0.77 to 1.00) 1.17 (1.01 to 1.35) 1.92 (1.79 to 2.06) 2.11 (1.85 to 2.40)

Values are presented as odds ratio (95% CI). Bold indicates P < 0.05 (logistic regression). Each row presents an individual logistic regression analytical model: Group 1 women (no FamHxMI/nonsmoker) was the reference group. Ever having had PD ~ individual RF + group 2 (FamHxMI/nonsmoker) + group 3 (no FamHxMI/smoker) + group 4 (FamHxMI/smoker) + interaction of RF group 2 + interaction of RF group 3 + interaction of RF group 4. All results from interaction of RF group 2 were nonsignificant and thus not presented in the table.

BMI, body mass index; CRP, C-reactive protein (natural logarithm transformed); FamHxMI, family history of myocardial infarction; HDL, high-density lipoprotein; HRT, hormone replacement therapy; ICAM, intercellular adhesion molecule 1; DM, diabetes; LDL, low-density lipoprotein; RF, risk factor.

a

Standardized serum levels (1-SD increase).