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. 2018 Oct 2;16:109. doi: 10.1186/s12915-018-0576-6

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© Lallemand et al. 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — VOPP1 expression in human breast tumors. a Real-time PCR analysis of VOPP1 expression in 448 breast tumors. The CGH profiles showing the VOPP1 chromosomal region are highlighted for two tumors. Statistical analysis was performed using the Mann-Whitney U test (***p < 0.001). b Representative images of an immunohistochemical analysis of VOPP1 protein expression in a series of 24 tumors. Arrows indicate the blood vessels. c Quantification of the immunohistochemical results showed in b. d Kaplan-Meier curves showing metastasis-free survival rates of patients with tumors expressing high (red line) vs. low (blue line) levels of VOPP1 mRNA