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. 2018 Oct;188(10):2281–2292. doi: 10.1016/j.ajpath.2018.06.011

Figure 1.

Figure 1

Histology and immunohistochemistry (IHC) of deep infiltrating endometriosis (DIE) lesion. Biopsies of DIE lesions were collected as described and stained with hematoxylin and eosin (H&E), CD68 (anti-macrophage), brain-derived neurotrophic factor (BDNF; anti-neurotrophin), PGP9.5 (anti-nerve fibers) antibodies, or nonimmune IgG as a negative control. Note that nerve fibers in the bottom middle panel are mostly viewed en face relative to the orientation of the DIE implant. Similar IHC findings were observed in all four patients with dominant DIE nodules. Original magnification, ×200.