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. 2018 Apr;93(4):903–920. doi: 10.1016/j.kint.2017.11.014

Figure S10.

Figure S10

Relative transcript levels of the Notch pathway components in primary podocytes of CreERTM−/−;Wt1f/f versus CreERTM+/−;Wt1f/f at day (D) 4 postinduction (PI) and D5 PI. (A) Notch pathway transcripts in D4 PI CreERTM+/−;Wt1f/f mutants compared with CreERTM−/−;Wt1f/f controls. Mean mRNA transcripts relative to Gapdh (± SEM, CreERTM−/−;Wt1f/f versus CreERTM+/−;Wt1f/f); Notch1: 1.1 ± 0.2 versus 0.9 ± 0.2 (P = 0.45); Notch2: 1.3 ± 0.3 versus 2.5 ± 0.8 (P = 0.18); Hes1: 2.8 ± 0.6 versus 3.5 ± 0.4 (P = 0.37); Hes5: 1.1 ± 0.2 versus 2.2 ± 0.9 (P = 0.27); HeyL: 1.4 ± 0.6 versus 8.5 ± 5.4 (P = 0.23); Mfng: 1.8 ± 0.6 versus 7.8 ± 4.4 (P = 0.16), Student t-test. (B) Notch pathway transcripts in D5 PI CreERTM+/−;Wt1f/f mutants compared with CreERTM−/−;Wt1f/f controls: Notch1: 1.3 ± 0.2 versus 1.2 ± 0.29 (P = 0.88); Notch2: 1.5± 0.16 versus 1.9 ± 0.31 (P = 1.47); Hes1: 2.5 ± 0.4 versus 2.2 ± 0.5 (P = 0.73); Hes3: 1.2 ± 0.1 versus 0.88 ± 0.09 (P = 0.05); Hes5: 1.5 ± 0.6 versus 1.3 ± 0.25 (P = 0.8); HeyL: 2.5 ± 0.97 versus 2.6 ± 0.8 (P = 0.9); Mfng: 1.8 ± 0.6 versus 7.8 ± 4.4 (P = 0.16), Student t-test.