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. 2018 Jul 2;99(3):697–703. doi: 10.4269/ajtmh.18-0137

Table 4.

Distribution of major epitopes in pfhrp2 sequences

Major epitope This study (N = 18) Previous studies (N = 15) MAb*
Prevalence Average frequency Prevalence Average frequency
% (n) % % (n) %
DAHHAHHA 100 (18) 18 100 (15) 18 3A4, PTL-3
DAHHAADAHH 94 (17) 8 100 (15) 7 2G12-1C12
DAHHVADAHH 0 (0) 0 0 (0) 0 2G12-1C12
YAHHAHHA 94 (17) 4 100 (15) 4 1E1-A9, PTL-3
DAHHAHHV 89 (16) 5 100 (15) 3 1E1-A9
HATDAHHAAD 61 (11) 2 67 (10) 3 A6-4
HATDAHHAAA 67 (12) 2 100 (15) 2 A6-4
AHHAADAHHA 100 (18) 26 100 (15) 26 C1-13
DAHHAADAHHA 94 (17) 8 100 (15) 7 N7
AHHAADAHH 100 (18) 26 100 (15) 26 S2-5, C2-3
AHHASDAHH 78 (14) 2 100 (15) 2 S2-5
TDAHHAADAHHAADA 50 (9) 1 53 (8) 1 TC-10
AAYAHHAHHAAY 0 (0) 0 0 (0) 0 Genway

MAb = monoclonal antibody; pfhrp2 = Plasmodium falciparum histidine-rich protein 2 gene.

*

Lee et al.18