Table 3. Details for influenza A and B in cases and control aged 65 years and older, test–negative influenza case–control study, United Kingdom, influenza seasons 2010/11–2016/17.
Characteristics | Controls | Percent | Influenza type | |||||||
---|---|---|---|---|---|---|---|---|---|---|
B | Percent | A(H1N1)pdm09 | Percent | A(H3N2) | Percent | A (Unknown) | Percent | |||
Schemea | ||||||||||
Northern Ireland | 64 | 65.3 | 4 | 4.1 | 3 | 3.1 | 20 | 20.4 | 7 | 7.1 |
RCGP (England) | 831 | 80.9 | 51 | 5.0 | 36 | 3.5 | 107 | 10.4 | 2 | 0.2 |
SMN (England) | 122 | 89.1 | 3 | 2.2 | 3 | 2.2 | 9 | 6.6 | 0 | 0.0 |
Scotland | 652 | 83.3 | 39 | 5.0 | 11 | 1.4 | 70 | 8.9 | 11 | 1.4 |
Wales | 33 | 64.7 | 4 | 7.8 | 4 | 7.8 | 9 | 17.6 | 1 | 2.0 |
Sex | ||||||||||
Female | 1,040 | 81.6 | 53 | 4.2 | 30 | 2.4 | 137 | 10.8 | 14 | 1.1 |
Male | 655 | 80.5 | 48 | 5.9 | 27 | 3.3 | 77 | 9.5 | 7 | 0.9 |
Missing | 7 | 87.5 | 0 | 0.0 | 0 | 0.0 | 1 | 12.5 | 0 | 0.0 |
Age group | ||||||||||
65–74 | 1,084 | 81 | 76 | 5.7 | 42 | 3.1 | 124 | 9.3 | 13 | 1.0 |
75–84 | 487 | 87.2 | 21 | 3.6 | 12 | 2.0 | 64 | 10.9 | 5 | 0.8 |
≥ 85 | 131 | 78 | 4 | 2.4 | 3 | 1.8 | 27 | 16.1 | 3 | 1.8 |
Montha | ||||||||||
October | 218 | 98.6 | 1 | 0.5 | 0 | 0.0 | 1 | 0.5 | 1 | 0.5 |
November | 283 | 98.3 | 3 | 1.0 | 1 | 0.3 | 1 | 0.3 | 0 | 0.0 |
December | 397 | 80.4 | 21 | 4.3 | 15 | 3.0 | 61 | 12.3 | 0 | 0.0 |
January | 400 | 77.5 | 27 | 5.2 | 18 | 3.5 | 66 | 12.8 | 5 | 1.0 |
February | 223 | 69.9 | 21 | 6.6 | 11 | 3.4 | 58 | 18.2 | 6 | 1.9 |
March | 130 | 65.0 | 24 | 12.0 | 12 | 6.0 | 25 | 12.5 | 9 | 4.5 |
April | 51 | 87.9 | 4 | 6.9 | 0 | 0.0 | 3 | 5.2 | 0 | 0.0 |
Onset of symptoms to swaba | ||||||||||
0–1 days | 165 | 77.1 | 7 | 3.3 | 7 | 3.3 | 33 | 15.4 | 2 | 0.9 |
2–4 days | 766 | 78.1 | 55 | 5.6 | 31 | 3.2 | 116 | 11.8 | 13 | 1.3 |
5–7 days | 771 | 85.6 | 39 | 4.3 | 19 | 2.1 | 66 | 7.3 | 6 | 0.7 |
Influenza seasona | ||||||||||
2010/11 | 222 | 84.7 | 24 | 9.2 | 16 | 6.1 | 0 | 0.0 | 0 | 0.0 |
2011/12 | 232 | 91.7 | 2 | 0.8 | 0 | 0.0 | 19 | 7.5 | 0 | 0.0 |
2012/13 | 196 | 73.1 | 32 | 11.9 | 0 | 0.0 | 38 | 14.2 | 2 | 0.7 |
2013/14 | 144 | 92.9 | 0 | 0.0 | 0 | 0.0 | 3 | 1.9 | 8 | 5.2 |
2014/15 | 249 | 70.9 | 12 | 3.4 | 1 | 0.3 | 84 | 23.9 | 5 | 1.4 |
2015/16 | 346 | 84.6 | 19 | 4.6 | 39 | 9.5 | 4 | 1.0 | 1 | 0.2 |
2016/17 | 313 | 78.6 | 12 | 3.0 | 1 | 0.3 | 67 | 16.8 | 5 | 1.3 |
Vaccinationa | ||||||||||
Unvaccinated | 551 | 82.4 | 41 | 6.1 | 28 | 4.2 | 44 | 6.6 | 5 | 0.7 |
14–91 days before onset | 666 | 87.7 | 13 | 1.7 | 11 | 1.4 | 66 | 8.7 | 3 | 0.4 |
> 92 days before onset | 485 | 72.6 | 47 | 7.0 | 18 | 2.7 | 105 | 15.7 | 13 | 1.9 |
RCGP: Royal College of General Practitioners Research and Surveillance Centre; SMN: specialist regional microbiology laboratories.
a P value was < 0.001.