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Effects of chronic sugar exposure on systemic inflammatory profile. Plasma levels of TNF-α (a), IL-1β (b), and IL-6 (c) were measured in mice fed for 24 weeks with a control diet or with a diet containing liquid or solid supplementation of fructose/D-tagatose. Values are represented as means ± S.E.M. of 6 animals per group. ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001, vs. CD. ## and ### denote, respectively, p < 0.01 and p < 0.001 vs. corresponding Tg formulation.
