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. Author manuscript; available in PMC: 2018 Oct 3.
Published in final edited form as: Reprod Toxicol. 2018 May 9;79:39–46. doi: 10.1016/j.reprotox.2018.05.002

Table 2.

Comparison of fertility of exposed females after a single mating with an unexposed male. Fertility at 3, 6 or 9 months of age is expressed as the % of animals producing litters. Increased age of dam resulted in decreased fertility across all treatment groups. There was a pronounced decline in fertility between 3 and 9 months in the BPA 250 ng animals, but this decline did not reach significance. Only females exposed perinatally to DES exhibited a significant decrease in fertility at 9 months compared to age-matched controls (*p < 0.05; χ2 analysis).

Treatment 3 month
 6 month
 9 month
n % fertility N % fertility N % fertility
Vehicle 37 100 29 79 21 57
25 ng BPA 25 90 26 77 16 44
250 ng BPA 33 100 27 81 16 25
25 μg BPA 30 100 26 69 18 39
10 ng DES 29 100 27 74 20 20*