Table 1.
Baseline Characteristics of the Patient Population
| Variable | Overall Population (N = 101) |
BPA Success Group (n = 86) |
BPA Failure Group (n = 15) |
P Valuea |
|---|---|---|---|---|
| Baseline characteristics | ||||
| Age, y | 63.4 ± 13.8 | 62.9 ± 13.8 | 66.1 ± 13.8 | .392 |
| Male | 54 (53.5%) | 45 (52.3%) | 9 (60.0%) | .582 |
| BAA, mm2 | 8.4 [6.4-11.2] | 8.7 [6.9-11.3] | 6.7 [5.3-10.0] | .043 |
| NYHA functional class (I, II/III, IV), % | 26.6/73.4 | 27.9/72.1 | 20.0/80.0 | .753 |
| 6MWD, m | 399 ± 116 | 408 ± 111 | 376 ± 79 | .359 |
| Subpleural perfusion (poorly perfused) | 19 (18.8%) | 12 (13.9%) | 7 (46.7%) | .003 |
| Dlco, % | 61.8 ± 13.6 | 63.1 ± 12.8 | 54.9 ± 15.7 | .035 |
| Baseline hemodynamics | ||||
| Mean RAP, mm Hg | 8.1 ± 3.7 | 8.1 ± 3.6 | 8.4 ± 4.4 | .747 |
| Systolic PAP, mm Hg | 78.4 ± 17.4 | 78.7 ± 18.1 | 76.3 ± 12.4 | .633 |
| Diastolic PAP, mm Hg | 25.3 ± 7.9 | 24.9 ± 7.8 | 27.4 ± 8.1 | .267 |
| Mean PAP, mm Hg | 45.6 ± 10.3 | 45.5 ± 10.4 | 46.1 ± 10.2 | .827 |
| PAWP, mm Hg | 9.5 ± 3.6 | 9.6 ± 3.7 | 8.7 ± 2.8 | .375 |
| DPG, mm Hg (diastolic PAP-PCWP) | 15.8 ± 8.3 | 15.3 ± 8.5 | 18.7 ± 6.4 | .147 |
| Cardiac output, L/min | 4.65 ± 1.22 | 4.61 ± 1.15 | 4.88 ± 1.60 | .425 |
| Cardiac index, L/min/m2 | 2.53 ± 0.51 | 2.52 ± 0.49 | 2.60 ± 0.69 | .582 |
| PVR, Wood unit | 8.30 ± 3.16 | 8.32 ± 3.27 | 8.21 ± 2.47 | .886 |
| Svo2, % | 61.7 ± 7.2 | 62.3 ± 7.2 (n = 62) |
58.1 ± 6.2 (n = 11) |
.072 |
| PH medical treatment at baseline | ||||
| No treatment/monotherapy/double combination/triple combination therapy, % | 46/23/27/4 | 48/22/26/4 | 33/27/33/7 | .585 |
Data are presented as mean SD or median [interquartile range] unless otherwise indicated. 6MWD = 6-min walk distance; BAA = bronchial arterial area; BPA = balloon pulmonary angioplasty; DPG = diastolic pressure gradient; Dlco = diffusing capacity for carbon monoxide; NYHA = New York Heart Association; PAP = pulmonary arterial pressure; PAWP = pulmonary artery wedge pressure; PCWP = pulmonary capillary wedge pressure; PH = pulmonary hypertension; PVR = pulmonary vascular resistance; RAP = right atrial pressure; Svo2 = mixed venous oxygen saturation.
a
Comparison between operable and nonoperable patient populations.