Table 3.
Baseline Characteristics and Treatments in Patients From the Normally Perfused Group and the Poorly Perfused Group
| Variable | Normally Perfused (n = 82) |
Poorly Perfused (n = 19) |
P Value |
|---|---|---|---|
| Baseline characteristics | |||
| Age, y | 63.6 ± 13.9 | 62.5 ± 13.8 | .765 |
| Male | 42 (51.2%) | 12 (63.2%) | .374 |
| BAA, mm2 | 8.7 [6.9-11.3] | 7.0 [5.8-9.6] | .032 |
| NYHA functional class (I, II/III, IV), % | 32.0/68.0 | 5.3/94.7 | .018 |
| 6MWD, m | 404 ± 114 | 378 ± 174 | .421 |
| Dlco, % | 63.3 ± 13.7 | 55.9 ± 11.4 | .037 |
| Baseline hemodynamic variables | |||
| Mean RAP, mm Hg | 8.0 ± 3.6 | 8.7 ± 4.1 | .458 |
| Systolic PAP, mm Hg | 77.8 ± 17.5 | 80.6 ± 17.1 | .543 |
| Diastolic PAP, mm Hg | 24.4 ± 7.9 | 29.1 ± 6.9 | .019 |
| Mean PAP, mm Hg | 44.9± 10.3 | 48.6 ± 9.7 | .161 |
| PAWP, mm Hg | 9.4 ± 3.8 | 9.8 ± 2.8 | .707 |
| DPG, mm Hg (diastolic PAP-PCWP) | 15.0 ± 8.4 | 19.3 ± 6.9 | .042 |
| Cardiac output, L/min | 4.71 ± 1.26 | 4.34 ± 1.03 | .246 |
| Cardiac index, L/min/m2 | 2.57 ± 0.52 | 2.34 ± 0.47 | .083 |
| PVR, Wood unit | 8.12 ± 3.20 | 9.03 ± 3.0 | .271 |
| Svo2, % | 62.4 ± 7.2 (n = 61) |
57.9 ± 6.2 (n = 12) |
.046 |
| PH medical treatment at baseline | |||
| No treatment/monotherapy/ double combination therapy/ triple combination therapy, % | 48/25/23/4 | 37/16/42/5 | .348 |
Data are presented as mean ± SD or median [interquartile range] unless otherwise indicated. See Table 1 legend for expansion of abbreviations.