Table 3.
Feature name | RFE rank |
---|---|
Seed site conservation | 1 |
Target site location in UTR | 2 |
GC content of target site | 3 |
UG count | 4 |
AG count | 5 |
UTR length | 6 |
Free energy of seed sequence binding | 7 |
Pentamer motif match | 8 |
GC content of 3′ end of target site | 9 |
GC content of upstream nucleotides of target site | 10 |
Position 1 A | 11 |
Position 9 U | 12 |
Position 1 G | 13 |
CG count | 14 |
Position 13 G | 15 |
UA count | 16 |
Position 11 G | 17 |
AC count | 18 |
A count | 19 |
Position 9 C | 20 |
Position 12 G | 21 |
Target site <200 n.t. to UTR end | 22 |
Position 10 AU | 23 |
AA count | 24 |
Position 1 AU | 25 |
GG count | 26 |
Position 16 G | 27 |
GA count | 28 |
Position 14 G | 29 |
Position 9 A | 30 |
Position 13 C | 31 |
Position 9 AU | 32 |
Position 13 AU | 33 |
C count | 34 |
CU count | 35 |
AU count | 36 |
CC count | 37 |
Position 12 C | 38 |
Position 11 AU | 39 |
Position 0 G | 40 |
Position 11 C | 41 |
Position 15 G | 42 |
GU count | 43 |
Position 16 U | 44 |
UC count | 45 |
CA count | 46 |
Position 16 C | 47 |
G count | 48 |
Target site > 800 n.t. to UTR end | 49 |
Position 11 U | 50 |
aTop-ranking target recognition features were identified by SVM-RFE. The seed-binding site is designated as positions 2–8. These features were summarized by analysis of target sites in 3′-UTR sequences.