Table 2.

Anti-influenza activities of different extracts of Seabuckthorn leaf.

	A/PR			A/Victoria		B/Lee		B/Maryland
	CC50a	IC50b	TIc	IC50	TI	IC50	TI	IC50	TI
Methanol	155.8	7.2 ± 0.2	21.7	8.39 ± 0.89	18.5	6.39 ± 0.89	24.3	9.29 ± 0.89	16.8
Ethyl Acetate	558.2	10.31 ± 0.3	54.4	8.86 ± 0.35	62.9	2.87 ± 0.35	194.5	4.52 ± 0.35	123.5
Butanol	62.1	14.3 ± 1.1	4.2	15.97 ± 0.15	3.9	5.97 ± 0.15	10.4	6.81 ± 0.15	9.1
Water	917.6	40.8 ± 4.9	22.5	58.87 ± 0.02	15.6	8.87 ± 0.02	103.4	21.7 ± 3.1	42.3
Oseltamivir	569.1	60.3 ± 5.6	9.5	37.2 ± 3.5	15.3	103.7 ± 8.75	5.5	71.6 ± 5.1	8.0

Each value was obtained from an average of three independent experiments’ standard deviation.

^aConcentration required to reduce MDCK cell growth by 50% (μg/mL).

^bConcentration required to inhibit virus infectivity by 50% (μg/mL).

^cTherapeutic index = CC₅₀/IC₅₀.