Figure 4.
Adoptive transfer of effector CD8 + T cells from vaccine and anti-4-1BB-treated mice induced protection against AML-ETO9a tumor challenge.. Mice either received no CD8 + T cell transfer (A), naïve CD8 + T cells (B), unfractionated CD8 + T cells from untreated tumor-bearing mice (C) or from TCM (D) and TEM (E) from mice previously treated with vaccine plus anti-4-1BB followed by determination of tumor growth displayed as individual curves. Summary data of tumor burden at day 41 is shown (F) and presented as mean ± SEM, analyzed by One-way ANOVA to determine the significance; * p < 0.05.