Figure 6.

The vaccine and anti-4-1BB combination therapy eradicates established MLL-AF9 tumors.. Mice were administered with MLL-AF9 tumor cells followed by vaccine and anti-4-1BB therapy. Indicated are dot plots of representative data displaying the levels and percent blood tumor (day 28) from control and experimental mice (A), GFP⁺ MLL-AF9 tumor cells in the blood (B, C) and mouse survival curves (D). Tumor data is displayed as individual curves (n = 5), and survival curves were analysed by the Mantel-Cox log-rank multiple comparison test to determine significance (p < 0.05). Dot plots were analysed by Kaluza analysis program. **p < 0.01.