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. 2018 Oct 1;3(5):e000866. doi: 10.1136/bmjgh-2018-000866

Table 2.

Cluster risk factors and determinants of preventable non-communicable chronic diseases

Risk and protective factors Biological risk factors/markers Preventable chronic disease and conditions
Behavioural factors
  • Diet.

  • Physical activity.

  • Smoking.

  • Alcohol misuse.


Psychosocial factors
  • ‘sense of control’.

  • Social support/social exclusion.

  • Resilience and emotional well-being.


Early life factors
  • Maternal health.

  • Low birth weight.

  • Childhood infections.

  • Abuse and neglect.

  • Obesity.

  • Hypertension.

  • Dyslipidaemia.

  • Impaired glucose regulation.

  • Proteinuria.

  • Ischaemic heart disease.

  • Stroke.

  • Type 2 diabetes.

  • Renal disease.

Non-modifiable factors: age, sex, ethnicity, genetic make-up and family history.

Socioenvironmental determinants (may or may not be modifiable): socioeconomic status, community characteristics (eg, presence/absence of social capital), work conditions, environmental health and so on.