Table 1. Electrophysiological markers evaluated in the proposed response surface approximation-based optimization.

	Physiol. Range	Selected Range	CRLP Model	This work
APD90 (ms)	271-366	280-310	305.6	280.9
Triangulation (ms)	44-112	44-112	78	84.6
Sys. [Ca2+]i 1Hz (μM)	1.59-2.01	0.602-2.01	0.602	0.701
Sys. [Ca2+]i 0.5Hz (μM)	0.71-1.68	0.523-1.68	0.523	0.664
Dia. [Ca2+]i 1Hz (μM)	0.20-0.33	0.097-0.33	0.097	0.100
Dia. [Ca2+]i 0.5Hz (μM)	0.14-0.32	0.091-0.32	0.091	0.096
τslow (s)	70-110	70-110	105.6	106.0
∫CL IK,tot ⋅ dt (ms ⋅ pA/pF)			-28.52	-3.9 ⋅ 10−9