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. 2018 Oct 3;13(10):e0204960. doi: 10.1371/journal.pone.0204960

Fig 11. Time-course gene expression analysis of BIRC5, CXCL8, CXCL10, CXCL12 and PTGS2 following 2 and 20 Gy irradiation of HUVECs.

Fig 11

Control and irradiated HUVEC mRNA levels of the 5 genes were measured by real-time quantitative PCR at 0.5, 1, 2, 3, 4, 14 and 21 days post-exposure at a single dose of 2 or 20 Gy, and at day 21 after the first fraction of 2 Gy (D21 Frac1) and day 21 after the last fraction of 2 Gy (D21 Frac2) for dose-fractionation experiments (mean +/- SD). Data analyzed by the two-tailed t-test and adjusted p-values (Benjamini-Hochberg procedure) (non-irradiated vs irradiated): *, p<0.05; **p<0.01; ***, p<0.001.