Table 2.

Relative risk (RR) of breast-cancer mortality with Mammography Screening

Author/Year	Accrual period	Study recruitment	Relative risk of breast-cancer mortality ≥50 years (Age, RR)	Relative risk of breast-cancer mortality <50 years (Age, RR)
(Nystrom, et al. 2002)	Up to 1996	247010 women Invited group 129750, Control group 117260	50–54y, 55–59y, 60–64y, 65–69y RR=0.95,0.76, 0.68, 0.69, respectively	-
(Bastardis-Zakas, et al. 2010)	1988–2006	Meta-analyses of eight randomized control trials	-	40–49y RR=0.81
(Moss, et al. 2006)	1963–1990	160,921 women	-	40–49y RR= 0·83 [95% CI 0·66–1·04], p=0·11
(Humphrey, et al. 2002)	1963–1982	Reviewed 154 publications from ten trials	≥ 50 y RR= 0.78 (95%CI, 0.70 to 0.87)	< 50 y RR=0.85 95%CI, 0.73 to 0.99)
(Nelson, et al. 2009)	1986–2006	Meta-analysis of seven Mammography Screening Trials	50–59y RR=0.86 (0.75–0.99) 60–69y RR= 0.68 (0.54–0.87)	39–49y RR=0.85(0.75–0.96
(Donna Fitzpatrick-Lewis 2011)	2008–2010	Systematic review Randomized controlled trials	50–69y seven studies RR=0.79(0.68–0.90) ≥ 70y two trials RR=0.68(0.45–1.01)	Eight trials 39–49y RR=0.85 (0.75–0.96) two trials 39–49y RR=0.97(0.91–1.04)
(Miller, et al. 2014)	1980–85 25-year- follow up	89,835 women Randomized controlled trials	40–59y hazard ratio 1.05 (0.85 to 1.30) The findings for women aged 40–49 and 50–59 were almost identical
(Hamashima, et al. 2015)	1985 – 2014	Randomized controlled trials on PubMed and other databases	40–74 years without clinical breast examination RR=0.75 40–64 years with clinical breast examination RR= 0.87