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. Author manuscript; available in PMC: 2018 Oct 3.
Published in final edited form as: Cell Rep. 2018 Sep 11;24(11):3045–3060.e5. doi: 10.1016/j.celrep.2018.08.030

Figure 4. Lack of STIM1 and STIM2 in Leukemic T Lymphoblasts Protects Mice from Anemia.

Figure 4.

(A and B) Representative flow cytometry plots of erythropoietic precursor cells in the BM (A) and spleen (B) of mice with WT and Stim1/2−/− leukemia at day 21 of disease. Bar graphs show percentages and absolute numbers of Ter119+ forward scatter (FSC) high erythropoietic precursor cells in mice with WT and Stim1/2−/− leukemia as well as healthy WT control mice (ctrl). Data are representative of five to eight mice per group. n/a, not applicable (no cells available for analysis).

(C) Hemoglobin levels in the blood of healthy WT control mice (ctrl) and mice with WT and Stim1/2−/− leukemia. RV, range of reference values. Each dot represents a single mouse.

Cell numbers (A and B) and Hb levels (C) at days 21 and 24 of disease (D21/ D24) were combined. All values represented by bar graphs (A and B) and dot plots (C) are mean ± SEM. Statistical analysis was performed using Student’s t test. *p < 0.05.