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. Author manuscript; available in PMC: 2018 Oct 3.
Published in final edited form as: J Allergy Clin Immunol. 2017 Feb 10;140(6):1651–1659.e1. doi: 10.1016/j.jaci.2016.12.974

FIG 5.

FIG 5

Normal T-cell function in ebo/ebo mice. A–C, Proliferation (Fig 5A) and secretion of IL-2 (Fig 5B) and IFN-γ (Fig 5C) by splenic T cells from WT and ebo/ebo mice in response to stimulation with immobilized anti-CD3 mAb, anti-CD3 plus anti-CD28 mAbs, or anti-CD3 mAb plus IL-2. D-F, Proliferation (Fig 5D) and secretion of IL-2 (Fig 5E) and IFN-γ (Fig 5F) by splenic T cells from WT and ebo/ebo mice in response to stimulation with KLH. High- and low-affinity TNP-specific serum antibody titers in KLH-TNP–immunized WT and ebo/ebo mice are shown. Results in Fig 5, A–C, are pooled from 1 experiment with 3 mice per group. Similar results were obtained in 3 other experiments with 1 mouse per group each. Results in Fig 5, D–H, are pooled from 3 experiments with 4 mice per group. Columns/lines and bars represent means and SEMs.